Possible Interaction: Potassium and Tetraethylammonium

“Blockade of the potassium delayed rectifier current by tetraethylammonium (5 mm) or the hyperpolarization‐activated current (Ih) by ZD7288 (10 μm) disrupted the synchronization of the potassium‐induced oscillation.”

“Substitution of impermeant ions for potassium and blocking of the channel conductance with tetraethylammonium allows the recording of potassium gating currents, Ig, which is hampered in natural excitable cells by the simultaneous presence of sodium channels and a variety of different potassium channels.”

“However, tetraethylammoniumchloride , an inhibitor of Ik, was ineffective to block apoptosis after potassium withdrawal.”

“Blocking potassium currents with tetraethylammonium and replacing chloride ions with methanesulfonate did not unmask an inward current.”

“Mouse zygotes exposed to 200 μM H2O2 exhibited potassium efflux that elevated the potassium concentration of the media surrounding embryos by 1.4 ± 0.1 μM. Pretreatment with tetraethylammonium inhibited this increase (0.2 ± 0.1 μM).”

“Manipulating potassium currents with 1.0 mM tetraethylammonium or elevating potassium ion concentration to 7.5 mM altered evoked responses but did not replicate the injury effects to PV duration.”

“The tachykinin substance P could reduce inward and outward rectification in the dorsal cells, the effect on outward rectification only being seen when potassium conductances were blocked by tetraethylammonium (TEA).”

“The potassium current was blocked by tetraethylammonium , 4-aminopyridine, barium and cobalt.”

“This potassium current was partially blocked by 20 mM tetraethylammonium ions.”

“ Tetraethylammonium and 4-aminopyridine effectively blocked potassium outward currents but failed to distinguish this calcium-dependent potassium channel from the other two potassium channels in this preparation.”