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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Potassium and Succinylcholine



Research Papers that Mention the Interaction

The ICU length of stay before giving succinylcholine could influence significantly the amplitude of potassium increase.
Annales francaises d'anesthesie et de reanimation  •  2012  |  View Paper
These results indicate that IV thiamylal and ketamine both suppress the increases of myoglobin, CK, and potassium, and that in cases when succinylcholine is used, both drugs can help to avoid myoglobinemia and limit the increases of CK and potassium. (
Anesthesia and analgesia  •  1995  |  View Paper
A significant increase in plasma potassium concentration was observed following the administration of suxamethonium.
British journal of anaesthesia  •  1976  |  View Paper
Mean arterial potassium increased 84 per cent in 14 massively traumatized soldiers following administration of succinylcholine , 1 mg/kg, for intubation.
Anesthesiology  •  1969  |  View Paper
Both succinylcholine and a nonselective β-adrenergic blocker, propranolol, have the propensity to affect the transcellular redistribution of potassium which can result in hyperkalemia.
Drug metabolism and personalized therapy  •  2015  |  View Paper
ConclusionSuccinylcholine was associated with a modest increase in potassium concentration; these changes were not seen after rocuronium or sugammadex (Clinical trial registration number: NCT00751179).RésuméContexteLa succinylcholine entraîne l’installation rapide d’un blocage neuromusculaire avec une courte durée d’action, mais son administration peut être associée à une hyperkaliémie.
Canadian Journal of Anesthesia/Journal canadien d'anesthésie  •  2014  |  View Paper
A study by Martyn and Richtsfeld explained the phenomenon of proliferation of acetylcholine receptors on the muscle membrane in neuropathies, which can cause massive release of potassium on exposure to succinylcholine.
British journal of anaesthesia  •  2013  |  View Paper
Suxamethonium causes an efflux of potassium (K+) ions by depolarizing acetylcholine receptors within the neuromuscular junction and produces a transient, small rise in serum K+ concentration in normal individuals that is usually of little clinical importance.
British journal of anaesthesia  •  2007  |  View Paper
Succinylcholine increases plasma potassium , especially in patients with nerve damage, and arrhythmias may be observed.
Medical toxicology and adverse drug experience  •  1989  |  View Paper
Keneally and Bush reported that potassium increased by an average of 0.23 mEq/L following succinylcholine after thiopental induction (4 mg/kg) in children less than 5 yr old (9).
Anesthesia and analgesia  •  1984  |  View Paper
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