supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Potassium
drug:
Succinylcholine
Research Papers that Mention the Interaction
“The ICU length of stay before giving succinylcholine could influence significantly the amplitude of potassium increase.”
[Changes in kaliemia following rapid sequence induction with succinylcholine in critically ill patients].“These results indicate that IV thiamylal and ketamine both suppress the increases of myoglobin, CK, and potassium, and that in cases when succinylcholine is used, both drugs can help to avoid myoglobinemia and limit the increases of CK and potassium. (”
“A significant increase in plasma potassium concentration was observed following the administration of suxamethonium.”
“Mean arterial potassium increased 84 per cent in 14 massively traumatized soldiers following administration of succinylcholine , 1 mg/kg, for intubation.”
“Both succinylcholine and a nonselective β-adrenergic blocker, propranolol, have the propensity to affect the transcellular redistribution of potassium which can result in hyperkalemia.”
“ ConclusionSuccinylcholine was associated with a modest increase in potassium concentration; these changes were not seen after rocuronium or sugammadex (Clinical trial registration number: NCT00751179).RésuméContexteLa succinylcholine entraîne l’installation rapide d’un blocage neuromusculaire avec une courte durée d’action, mais son administration peut être associée à une hyperkaliémie.”
“A study by Martyn and Richtsfeld explained the phenomenon of proliferation of acetylcholine receptors on the muscle membrane in neuropathies, which can cause massive release of potassium on exposure to succinylcholine.”
“ Suxamethonium causes an efflux of potassium (K+) ions by depolarizing acetylcholine receptors within the neuromuscular junction and produces a transient, small rise in serum K+ concentration in normal individuals that is usually of little clinical importance.”
“ Succinylcholine increases plasma potassium , especially in patients with nerve damage, and arrhythmias may be observed.”
“Keneally and Bush reported that potassium increased by an average of 0.23 mEq/L following succinylcholine after thiopental induction (4 mg/kg) in children less than 5 yr old (9).”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback