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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Potassium
drug:
Sodium Fluoride
Research Papers that Mention the Interaction
“In the erythrocytes, a five-minute exposure to 10 mM NaF caused a 50% increase in extracellular potassium concentrations after 12 hours compared to control erythrocyte suspensions (P less than .001).”
Sudden cardiac death from acute fluoride intoxication: the role of potassium.“At high concentrations of sodium fluoride there was an increased leak of potassium from platelets, which was further augmented by addition of calcium to the medium.”
“Contrarily, NaF in higher concentrations produced an inhibition of contractile tension associated with a shortening of action potential, an increase in potassium conductance, and an inhibition of calcium response.”
Dual effects of fluoride on the action potential, contraction, and membrane currents in frog atrial muscle.
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