Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 8 months ago

Possible Interaction: Potassium and Sodium Chloride



Research Papers that Mention the Interaction

It is concluded that infusion of 7.5% NaCl in a clinical relevant dose increases plasma potassium and causes minor changes in the acid‐base balance in normovolaemic women.
Scandinavian journal of clinical and laboratory investigation  •  2005  |  View Paper
Salt-sensitive" hypertension responds particularly well, perhaps, in part, because supplementation with potassium increases the urinary excretion of sodium chloride.
American journal of physiology. Regulatory, integrative and comparative physiology  •  2006  |  View Paper
Potassium feeding reduces the hypertension resulting from concomitant NaCl feeding.
Journal of the Medical Association of Georgia  •  1980  |  View Paper
It is also known that potassium itself reduces the rise in blood pressure caused by sodium chloride intake and reduces the increased sympathetic postural response which is seen in people on lowsodium diets [3].
Arthritis Research & Therapy  •  2021  |  View Paper
These results indicate that potassium reduces the rise in blood pressure caused by sodium chloride and reduces the increased sympathetic postural response seen in people on a low sodium intake.
Drugs  •  2012  |  View Paper
Substituting potassium and/or magnesium salts for sodium chloride (NaCl) may enhance the feasibility of salt restriction and lower blood pressure beyond the sodium reduction alone.
Nutrition journal  •  2011  |  View Paper
Well-controlled human studies subsequently showed that the BP-rising effect of extremely high NaCl intake can be blunted by potassium supplementation.
Hypertension  •  2010  |  View Paper
Moreover, we found that co-administration of an alkalinizing salt of potassium (potassium citrate) with NaCl prevented NaCl from increasing urinary calcium excretion and bone resorption, as occurred with NaCl administration alone.
European journal of nutrition  •  2001  |  View Paper
Additional potassium prevents, in sodium-sensitive people and rats, the rise in BP caused by extra sodium chloride.
Nephron  •  1987  |  View Paper
Fractional excretion of potassium was reduced in response to sodium chloride loading.
The American journal of the medical sciences  •  1986  |  View Paper
Show More