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Last Updated: 8 months ago

Possible Interaction: Potassium and Serotonin



Research Papers that Mention the Interaction

In the aneurysm group, significantly stronger contractions were demonstrated upon exposure to potassium and 5-hydroxytryptamine.
Surgical neurology  •  1981  |  View Paper
Later it has been proved that a large amount of 5-HT injected in the vein of the back of the hand did not provoke pain, but highly increased the pain producing action of bradykinin and potassium (Sicuteri et al. 1965).
Headache  •  1972  |  View Paper
Thus, 5-HT enhances two different cation currents and reduces potassium currents.
Journal of neurobiology  •  2006  |  View Paper
In the presence of serotonin , increasing extracellular potassium concentration from 5.4 to 20 mmol/l depolarizes the cell membrane by +26.4±1.0 mV (n=11).
Pflügers Archiv  •  2004  |  View Paper
The potassium (25 mmol/l)-evoked tritium overflow from cortex synaptosomes was inhibited by 5-HT ; the inhibitory effect of 5-HT was counteracted by metitepine, which, by itself, did not affect the evoked overflow.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
The peak current of the potassium currents of the neuron treated with 5-&agr;-methylhydroxytryptamine was decreased.
These results suggest 5-&agr;-methylhydroxytryptamine increases spontaneous firing of the medial vestibular nuclear neurons by inhibiting calcium dependent potassium currents.
Neuroreport  •  2003  |  View Paper
5-HT also decreases the maximal conductance of a sustained potassium current [IK(V) ] without affecting its voltage dependence.
The Journal of Neuroscience  •  1999  |  View Paper
Local perfusion of the hypothalamus with dialysis solution containing 5-hydroxytryptophan (a 5-HT precursor), fluoxetine (a 5-HT reuptake inhibitor), or high potassium significantly increased both colonic temperature (Tco) and the extracellular concentrations of 5-HT in the hypothalamus.
The American journal of physiology  •  1998  |  View Paper
Addition of potassium (K+, 120 mM) to the perfusion fluid evoked an approximately 3-fold increase in 5-HT release.
Neuroscience Letters  •  1995  |  View Paper
Potassium induced dramatic release of serotonin.
Neuroscience Research  •  1995  |  View Paper
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