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Last Updated: 8 months ago

Possible Interaction: Potassium and Quinidine

supplement:

Potassium

supplement:

Quinidine

Research Papers that Mention the Interaction

Similarly, potassium decreased QTUc dispersion ( quinidine , 210+/-62 to 130+/-75 ms(1/2), P<.01; CHF, 132+/-68 to 84+/-35 ms(1/2), P=.07) and was without effect in the control subjects.
Circulation  •  1997  |  View Paper
The resulting potassium current showed outward rectification under physiological conditions and slight inward rectification with symmetrical high-K+ solutions and could be inhibited by application of halothane or quinidine.
Pflügers Archiv - European Journal of Physiology  •  2013  |  View Paper
Hence, the electrophysiologic action of quinidine was nullified by a low potassium concentration in both groups of experiments.
Lowering potassium to 0.8 mEq./L., in the presence of the same concentration of quinidine , significantly increased the maximal rate of depolarization (+82.5%), the height of action potential (+8.5%) and resting potential (+9.9%).
The American journal of cardiology  •  1963  |  View Paper
Antiarrhythmic drugs … quinidine , disopyramide), class III (sotalol, amiodarone), class IV (calcium … blockers) used at the same time with potassium depleters diuretics or beta-blocking agents result in the inhibition of repolarization and the increased duration … activation potential with the risk of developing arrhythmia of the torsade de pointes types.
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego  •  2000  |  View Paper
The potassium that moves through the Gardos pathway, on the other hand, can be accompanied by any permeant anion, and is inhibitable by quinidine or cetiedil.
American journal of hematology  •  1984  |  View Paper
It is concluded that quinidine reduces the membrane conductances for sodium, calcium, and potassium ions.
Journal of cardiovascular pharmacology  •  1979  |  View Paper
However, quinidine also blocks other potassium currents, such as Ito, and the degree of I(Kr) blockade with E4031 was probably greater than that with the same dose of quinidine.
Proceedings of the Western Pharmacology Society  •  2004  |  View Paper
The potassium channel blockers quinidine and glibenclamide afforded some protection against hypoxic injury, although their effects on cellular potassium were equivocal.
Pflügers Archiv  •  2004  |  View Paper
Quinidine (0.1‐1 mM) and tetraethylammonium ion (TEA) (10‐50 mM), blocked the potassium current in a dose‐dependent manner.
The Journal of physiology  •  1993  |  View Paper
Volume regulatory release of potassium is impaired in 1 mmol/L quinidine , 1 mmol/L SITS and 5 mmol/L barium.
Hepatology  •  1990  |  View Paper
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