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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Potassium
drug:
Eplerenone
Research Papers that Mention the Interaction
“Plasma potassium concentration achieved on eplerenone (4.30 ± 0.45 mmol/l) was significantly greater than on LCI699 (3.89 ± 0.35 mmol/l; P = 0.009).”
Sequential comparison of aldosterone synthase inhibition and mineralocorticoid blockade in patients with primary aldosteronism“Plasma potassium levels were higher in the eplerenone group than those in the other two groups (p < .05).”
Effects of eplerenone on cerebral aldosterone levels and brain lesions in spontaneously hypertensive rats“2-(Hydroxymethyl)-N-[4-(methylsulfonyl)phenyl]-2′-(trifluoromethyl)biphenyl-4-carboxamide, SPI, and EPL elevated serum levels of potassium significantly in potassium-loaded rats at doses that increased MR inhibitory activity.”
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