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Last Updated: 8 months ago

Possible Interaction: Potassium and Digitalis

supplement:

Potassium

supplement:

Digitalis

Research Papers that Mention the Interaction

In clinical circumstances when renal potassium loss is to be prevented such as in patients receiving digitalis , the addition of a potassium-sparing diuretic to either a thiazide or furosemide will achieve the clinical goal of providing an effective diuresis while inhibiting potassium excretion.
Angiology  •  1976  |  View Paper
Among other factors, it is believed that the simultaneous administration of digitalis in heart patients potentiates the potassium depletion caused by diuretics.
Angiology  •  1969  |  View Paper
Cellular depletion of magnesium and potassium is associated with an increased risk of cardiac arrythmias and increases the risk of digitalis toxicity.
DICP : the annals of pharmacotherapy  •  1991  |  View Paper
Both distribution across cell membranes and/or renal excretion of potassium may be altered by pharmacologic agents such as diuretics, alpha- and beta-catechol antagonists and agonists, depolarizing agents, and digitalis.
The American journal of medicine  •  1986  |  View Paper
Digitalis and succinylcholine, by producing efflux of potassium from cells, may cause hyperkalemia.
Medicine  •  1981  |  View Paper
The low potassium values at the same time may possibly affect the sensitivity of digitalis.
Thoraxchirurgie, vaskulare Chirurgie  •  1975  |  View Paper
Digitalis reduces the amount of potassium in cells and this alters the excitability of the ventricles.
In the Journal this week two teams of investigators describe a further complication of potassium depletion associated with digitalis therapy-namely, atrial tachycardia with atrioventricular block.
Schweizerische medizinische Wochenschrift  •  1967  |  View Paper
3 Levine 4 suggested that potassium loss may precipitate various arrhythmias, particularly supraventricular tachycardia, in patients receiving and in patients not receiving digitalis.
Archives of internal medicine  •  1967  |  View Paper
Digitalis induces a loss of intracellular potassium.
American heart journal  •  1964  |  View Paper
Thus, one of the ways potassium counteracts digitalis arrhythmias is the progressive depression of idioventricular automaticity.
The American journal of cardiology  •  1963  |  View Paper
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