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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Potassium Citrate and Calcium Supplement

Research Papers that Mention the Interaction

Potassium citrate caused a decrease in urinary calcium and a significant increase in urinary citrate that resulted in a significant decrease in the urinary saturation of calcium oxalate.
The Journal of urology  •  1988  |  View Paper
During potassium citrate therapy, urinary calcium significantly declined from 154 +/- 47 mg/day to 99 +/- 23 mg/day (P less than 0.01) and urinary citrate rose from 398 +/- 119 mg/day to 856 +/- 103 mg/day (P less than 0.001).
Kidney international  •  1983  |  View Paper
Urinary calcium excretion decreased by a mean of 60 mg/day on potassium citrate therapy —a nearly 30 % decrease in urine calcium excretion.
Urolithiasis  •  2015  |  View Paper
Net calcium balance was significantly improved in participants taking potassium citrate 90 mmol/d compared to placebo (142 ± 80 mg/d on 90 mmol/d versus −80 ± 54 mg/d on placebo; p = 0.02).
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research  •  2013  |  View Paper
Another trial reported 391 mg (21 meq) Mg daily as a mixed salt, Mg potassium citrate , reduced calcium stone recurrence by 90%, similar to potassium citrate, but with better gastrointestinal tolerance.
Magnesium research  •  2005  |  View Paper
Long term treatment (… who formed calcium stones … PSC in a single evening dose of 3.75 or 5.0 g (n = 55) gave a stone free rate of 75 … 5.0 or 7.5 g were given in two or three doses (n = 17).(ABSTRACT TRUNCATED AT 400 WORDS)
Scandinavian journal of urology and nephrology. Supplementum  •  1990  |  View Paper
Potassium citrate appears to reduce calcium excretion in both types of hypercalciuric type I renal tubular acidosis.(ABSTRACT TRUNCATED AT 400 WORDS)
The Journal of urology  •  1989  |  View Paper
Potassium citrate caused a significant decrease in urinary calcium.
Metabolism: clinical and experimental  •  1987  |  View Paper
Potassium citrate caused a significant increase in urinary pH and urinary citrate, and a decrease in urinary calcium.
The Journal of urology  •  1985  |  View Paper
Calcium stone formation can be prevented by the use of different drugs with different mechanisms of action (thiazide diuretics, allopurinol, and potassium citrate ), but there is no ideal drug that is both risk free and well tolerated.
F1000Research  •  2016  |  View Paper