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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Potassium Chloride
supplement:
Quinidine
Research Papers that Mention the Interaction
“When quinidine was followed by potassium chloride , 2 out of 5 dogs developed a significant increase in pulse rate and blood pressure.”
Quinidine intoxication: an experimental study of the effect of molar sodium lactate and potassium chloride.“Propafenone (>/=3 microM), quinidine (>/=30 microM), disopyramide (>/=100 microM) and flecainide (>/=100 microM) but not the other drugs decreased the contraction induced by 30 mM KCl in a concentration-dependent manner.”
Antagonism by class I antiarrhythmic drugs of levcromakalim-induced relaxation in isolated rat aorta.“Furthermore, the inhibitory effect of quinidine also increased in aorta preincubated in 40 mM KCl , whereas the inhibitory effects of other antiarrhythmics were almost similar in 5 or 40 mM KCl solution.”
“The inhibitory effects of quinidine were significantly enhanced when the rings were preincubated in 40 mM KCl (depolarizing conditions), when compared to normally polarized rings.”
“The inhibitor effects of quinidine were significantly enhanced (P < 0.05) when the preparations were preincubated in 40 mm KCl (depolarizing) solution.”
“ Quinidine also had a smaller yet significant effect on constrictor response to KCl suggesting a possible second site of action.”
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