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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Potassium Chloride
supplement:
Procaine
Research Papers that Mention the Interaction
“From these observations, it is concluded that at low concentrations procaine acts … muscarinic receptors in the guinea-pig taenia caecum while high concentrations of procaine may depress the …, substance P and KCl by inhibiting the Ca-induced Ca release from the … by reducing the transmembrane Ca influx during depolarization.”
Inhibitory effects of procaine on the contractile responses of the guinea-pig Taenia caecum to acetylcholine, substance P and potassium chloride“3 Procaine , 0.5–10 mM, relaxed the sustained contractions induced by 65.4 mM KCl and 10−6 m noradrenaline in the aorta, and by 45.4 mM KCl, 10−6 m carbachol and 10−6 m histamine in the taenia.”
“5 Concentrations of 2.2 × 10−7 to 3.6 × 10−5m procaine reduced the effects of both 5‐HT and KCl and suppressed the maximum responses.”
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