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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Potassium Chloride
supplement:
Glutamic Acid
Research Papers that Mention the Interaction
“Exposure to high KCl or ionomycin provoked Ca(2+)-dependent Glu release that was likewise augmented in SOD1(G93A) mice.”
“After constant basal levels of amino acid release were obtained, exposure to a depolarizing concentration of KCl (30 mM) evoked 4.05-, 2.18- and 3.00-fold increases in release of glutamic acid (Glu), aspartic acid (Asp) and gamma-aminobutyric acid (GABA) from synaptosomes.”
“At 35 degrees C and in the presence of 10 mM KCl , the pKa values for Asp 7, Glu 19, and Asp 27 (< 2.6, 3.2, and < 2.3, respectively) are more than 1 pH unit below those for model compounds.”
“Exposure to a depolarizing concentration of KCl (30 mM) resulted in 1.7 to 3.6-fold increases in Asp, Glu and GABA release.”
Presynaptic inhibition by clonidine of neurotransmitter amino acid release in various brain regions.“Exposure in superfusion to a depolarizing concentration of KCl (30 mM) evoked 3-, 2- and 2-fold increases in Glu , Asp and GABA release, respectively.”
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