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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Potassium Chloride
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“In RASMC, EGCG (100 μM) did not modify basal generation of cAMP or cGMP, but significantly reversed the inhibitory effects of NA (1 μM) and high KCl (60 mM) on cAMP and cGMP production.”
“In addition, EGCG noncompetitively antagonized the contractions induced by NA (in 1.5 mM Ca2+‐containing solution) and Ca2+ (in depolarizing Ca2+‐free high KCl 60 mM solution).”
“In rat aortic smooth … cells (RASMC), EGCG (100 μM) reduced increases in cytosolic free Ca2+ concentration ([Ca2+]i) induced by angiotensin II (ANG II, 100 nM) and KCl (60 mM) in 1.5 mM CaCl2‐containing solution and by ANG II (100 nM) in the absence of extracellular Ca2+.”
Study of the mechanisms involved in the vasorelaxation induced by (−)‐epigallocatechin‐3‐gallate in rat aorta
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