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“Both U46619 (30 nM) and KCl (50 mM) increased MLC20 phosphorylation levels, which were inhibited by genistein and daidzein.”
“Furthermore, both genistein and daidzein decreased the amount of GTP RhoA activated by either U46619 or KCl.”
“The cumulative additions of U46619 or KCl increased vascular tension in a concentration-dependent manner, which were inhibited by pretreatment with genistein or daidzein.”