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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Potassium Chloride
supplement:
Biochanin A
Research Papers that Mention the Interaction
“ Biochanin A, but not glycitein, was able to block the vasoconstriction caused by KCl , CaCl2, serotonin, and U46619 in a dose-dependent manner.”
Biochanin A, the Most Potent of 16 Isoflavones, Induces Relaxation of the Coronary Artery Through the Calcium Channel and cGMP-dependent Pathway.“Pre-incubation with prunetin (3 and 10 μg/mL) inhibited vasoconstriction induced by the supply of Ca2+ in rat aortic rings pre-contracted with PE or KCl in a Ca2+-free Krebs–Henseleit (KH) buffer.”
Prunetin Relaxed Isolated Rat Aortic Rings by Blocking Calcium Channels“ Biochanin A caused concentration-dependent relaxation of denuded rings precontracted with KCl (6 x 10(-2) mol/L).”
“Contractile responses induced by phenylephrine (PE), KCl and CaCl2 were antagonized by 10-7~10-4 mol/L biochanin A. The transient contraction elicited by PE was significantly attenuated by 10-5 mol/L biochanin A in Ca2+-free medium.”
Endothelium-independent Vasorelaxant Effect of the Phyto-oestrogen Biochanin A on Rat Thoracic Aorta
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