Possible Interaction: Potassium and Calcium Supplement

“With calcium and potassium supplementation, the night urinary sodium excretion in children with salt sensitivity was significantly increased (P<0.01), and it is negatively correlated with the increase in blood pressure.”

“During intervention, calcium, magnesium, phosphorus, potassium , thiamin, riboflavin, and vitamins C and D increased (P < 0.01) in the group receiving food calcium but not in the placebo or supplement groups.”

“This issue is further complicated by the fact that the vegetable intake– induced decrease in bone resorption has been shown to be independent of acid–base changes and that potassium , but not sodium bicarbonate (i.e., the same anion) or citrate, administration reduces urinary calcium excretion.”

“Beside their negative coupling with adenylate cyclase, they are also coupled with potassium and calcium channels, leading to a decreased intracellular calcium concentration.”

“Concerns have arisen that overly generous consumption of sodium, caffeine and phosphate may be detrimental to bone, as may be low dietary intakes of potassium , especially when dietary calcium intakes are simultaneously in adequate.”

“Injured cells release potassium and neurotransmitters that depolarize neighboring cells and cause further calcium entry.”

“ Potassium and neurotransmitter release spreads the calcium load over many cells.”

“Stimulation of melanin-concentrating hormone-like immunoreactivity release from rat hypothalamic slices revealed that potassium in the presence of calcium stimulated melanin-concentrating hormone-like immunoreactivity release.”

“The association of potassium intake with blood pressure was relatively stronger than the associations for other nutrients, but the intake of potassium was so highly correlated with intakes of calcium , milk, and protein that it was not statistically possible to identify the independent association of potassium and blood pressure.”

“High potassium raised calcium in control SH-SY5Y cells and those treated with articaine, but lidocaine treatment significantly reduced the response.”

“ Potassium acts antagonistically towards sodium and calcium ions , contributes to a reduction of the volume of extracellular fluids and at the same time reduces muscle tension and permeability of cell membranes.”