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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Potassium
drug:
Bedaquiline
Research Papers that Mention the Interaction
“In particular, bedaquiline is a very lipophilic compound with an associated long terminal half-life and shows potent inhibition of the cardiac potassium hERG channel, resulting in QTc interval prolongation in humans that may result in cardiac arrhythmia.”
Synthetic Studies to Help Elucidate the Metabolism of the Preclinical Candidate TBAJ-876—A Less Toxic and More Potent Analogue of Bedaquiline
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