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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Polyunsaturated Fatty Acids
supplement:
Vitamin C
Research Papers that Mention the Interaction
“Supplementation with vitamins C + E resulted in decreased OS and increased fluidity and PUFA proportion in the membrane, both of which positively modulate (Na,K)-ATPase activity, accounting for the blood pressure reduction.”
Modulation of (Na,K)-ATPase activity by membrane fatty acid composition: therapeutic implications in human hypertension“However, combination therapy with PUFA and vitamins C and E reduced the incidence of POAF by 68% (OR: 0.32; 95%CI: 0.17-0.60; P=0.0005; I(2)=38%).”
“At a concentration of 10 mmol/1 ascorbic acid totally inhibits oxidative break-down of polyunsaturated fatty acids by radicals originating from hydrogen peroxide.”
“A correlation was found between excess consumption of fat, saturated fatty acids, cholesterol, sugar, deficiency in the diet of polyunsaturated fatty acids and vitamin C to the coronary heart disease prevalence.”
“A combination of ω-3 PUFA and AA treatment confers an additive effect in suppressing lipid peroxidation and improving myocardial function.”
“ω-3 PUFA and AA combined have lower MDA and 4-HNE modified proteins than alone (p < 0.05).”
Effects of ω-3 PUFA and ascorbic acid combination on post-resuscitation myocardial function.“ Vitamin C significantly reduced the % of PUFA and increased the % of saturated fatty acid (SFA) in the liver lipid.”
“ Ascorbic acid treatment increases the content of polyunsaturated fatty acids in the lung considerably, i.e. the pulmonary membrane fluidity decreases significantly in response to ascorbic acid.”
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