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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Polyunsaturated Fatty Acids
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“However, PUFA may potentiate the acute exercise effect on smooth muscle cell relaxation via L-type Ca2+ channel modifications.”
Effects of n-3 fatty acids and acute exercise on endothelium-dependent vasorelaxation in healthy rat aorta“5 It is concluded that PUFAs have two effects on the SR; they reduce the availability of calcium for uptake and they inhibit the release mechanism.”
“3 g Ca was inhibited by retinoids (all‐trans retinal) and by polyunsaturated fatty acids (PUFAs) such as arachidonic acid and docosahexaenoic acid, which are known to be released in the retina by exposure to light.”
“At the same time calcium also activates a polyunsaturated fatty acid oxygenase , possibly lipoxygenase, that converts the free fatty acids to hydroxy fatty acids.”
“Taken together with the presence of Ca2+-stimulated lipase, these results suggest that calcium regulates both the release of polyunsaturated fatty acids from cellular lipids and their subsequent oxidation.”
“Different metal ions such as Ca2+ , Zn2+ and Fe3+ could stimulate PUFA synthesis and up-regulate desaturase gene transcription, while Cu2+ inhibited desaturase gene expression and lipid accumulation.”
Differential expression of desaturase genes and changes in fatty acid composition of Mortierella sp. AGED in response to environmental factors.
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