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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Polyunsaturated Fatty Acids and Calcium Supplement

Research Papers that Mention the Interaction

However, PUFA may potentiate the acute exercise effect on smooth muscle cell relaxation via L-type Ca2+ channel modifications.
British Journal of Nutrition  •  2008  |  View Paper
5 It is concluded that PUFAs have two effects on the SR; they reduce the availability of calcium for uptake and they inhibit the release mechanism.
The Journal of physiology  •  2000  |  View Paper
3 g Ca was inhibited by retinoids (all‐trans retinal) and by polyunsaturated fatty acids (PUFAs) such as arachidonic acid and docosahexaenoic acid, which are known to be released in the retina by exposure to light.
The Journal of physiology  •  2000  |  View Paper
At the same time calcium also activates a polyunsaturated fatty acid oxygenase , possibly lipoxygenase, that converts the free fatty acids to hydroxy fatty acids.
Developmental biology  •  1985  |  View Paper
Taken together with the presence of Ca2+-stimulated lipase, these results suggest that calcium regulates both the release of polyunsaturated fatty acids from cellular lipids and their subsequent oxidation.
Developmental biology  •  1985  |  View Paper
Different metal ions such as Ca2+ , Zn2+ and Fe3+ could stimulate PUFA synthesis and up-regulate desaturase gene transcription, while Cu2+ inhibited desaturase gene expression and lipid accumulation.
Journal of the science of food and agriculture  •  2017  |  View Paper