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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Polyunsaturated Fatty Acids
drug:
Arsenic Trioxide
Research Papers that Mention the Interaction
“However, combined treatment with As2O3 and either PUFA significantly reduced cell viability in a dose-dependent manner with AA being the most potent As2O3 enhancer.”
“In conclusion, our study shows that also other PUFAs than DHA-and in particular the omega-6-PUFA AA--can be used as effective modulators of tumor cell chemosensitivity to clinically achievable concentrations of As2O3.”
Omega-3 and omega-6 polyunsaturated fatty acids enhance arsenic trioxide efficacy in arsenic trioxide-resistant leukemic and solid tumor cells.
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