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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Polyunsaturated Fatty Acids and Arachidonate

Research Papers that Mention the Interaction

In the present investigation, small amounts of polyunsaturated fatty acids added to an incubation mixture of platelet microsomes and arachidonate were found to significantly inhibit subsequent platelet aggregation.
The Journal of laboratory and clinical medicine  •  1976  |  View Paper
When comparing arachidonate and oleate, in assays with one or both fatty acids, the polyunsaturate showed at least threefold higher rates of incorporation into PI.
Biochemistry and cell biology = Biochimie et biologie cellulaire  •  1986  |  View Paper
The rapid increase and subsequent decrease in eicosanoid metabolite excretion after oral administration of arachidonate indicates that the dietary intake of polyunsaturated fatty acids may have a more rapid effect upon the endogenous production of eicosanoids than is generally recognized.
Prostaglandins  •  1985  |  View Paper