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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Polyunsaturated Fatty Acids
drug:
Antipsychotic Agents
Research Papers that Mention the Interaction
“HighlightsTelomerase level (TA) of PBMCs increased during n‐3 PUFA supplementation added to antipsychotics.”
Telomerase level increase is related to n-3 polyunsaturated fatty acid efficacy in first episode schizophrenia: Secondary outcome analysis of the OFFER randomized clinical trial“ PUFA modified the effect of antipsychotics on triglycerides (p=0.046).”
“Since the EPUFA metabolism can be altered by years of untreated illness or differentially altered by various antipsychotics , the significance of EPUFA membrane status to schizophrenia psychopathophysiology is unclear.”
“These data indicate that lower membrane AA and DHA most likely predate the illness and probably contribute to the onset of illness, and furthermore treatment with some antipsychotics may increase the levels of EPUFAs.”
“The n-6/n-3 PUFA ratio positively correlated with severity of psychotic and depressive symptoms.”
Relationship Between Polyunsaturated Fatty Acids and Psychopathology in the NEURAPRO Clinical Trial
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