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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Polyphenols
drug:
Uridine Triacetate
Research Papers that Mention the Interaction
“The GSPE mechanism may include a noncovalent interaction of polyphenols with proline residues in the proline-rich domain of tau , with Pin1 sites at P213 and P232 most seriously affected as judged by suppression of labeling.”
“Several phenothiazines (methylene blue, azure … B, and quinacrine mustard), polyphenols (myricetin, epicatechin 5-gallate, gossypetin, and 2,3,4,…′,4′-pentahydroxybenzophenone), and the porphyrin ferric dehydroporphyrin IX inhibited tau filament formation with IC50 values in the low micromolar range … assessed by thioflavin S fluorescence, electron microscopy, and Sarkosyl insolubility.”
Inhibition of Heparin-induced Tau Filament Formation by Phenothiazines, Polyphenols, and Porphyrins*
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