supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Polyphenols
supplement:
Serum Albumin, Human
Research Papers that Mention the Interaction
“Furthermore, some conformational changes of HSA could be observed in the presence of polyphenols.”
Protective effects of three structurally similar polyphenolic compounds against oxidative damage and their binding properties to human serum albumin.“The interaction of polyphenols with the main drug carrier in blood human serum albumin ( HSA ) showed decrease in its fluorescence intensity.”
“This study showed that small differences in the structure of polyphenols such as RES and RESAn1 influenced the thermodynamics and kinetics of the complex formation with HSA.”
“However, the glycation of HSA is believed to reduce the binding affinities for acidic drugs such as polyphenols and phenolic acids.”
“ Natural polyphenols are known to interact with HSA and some polyphenols have been shown to be potent inhibitors of amyloid fibrillation.”
“ HSA glycation is believed to reduce the binding affinities for acidic drugs such as dietary polyphenols and phenolic acids.”
“We observe that the gallate moiety of the polyphenols plays a crucial role in determining the mode of interaction with HSA.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback