Possible Interaction: Polypeptides and Rabbit Allergenic Extract

“… polypeptide … rabbit reticulocyte lysate system with an IC50 of 37.5 nM. This activity was preserved between pH 5 and pH 11, and between 10 and … 13 and at 70 degrees C. Antibacterial activity against Bacillus, Megabacterium, and Pseudomonas species and antiproliferative activity against leukemia L1210 cells were observed.”

“~ * ~ The rabbit is known to be particularly sensitive to the lipolytic effect of pituitary polypeptides.”

“ Rabbit antisera specific for these structurally defined polypeptide fragments of streptococcal M protein (pep M5, pep M6, and pep M24) blocked IFN induction by each of the polypeptides.”

“Previous reports have demonstrated that large cationic polypeptides (of molecular mass 5,000 daltons or greater) cause an increase in the apical membrane conductance of the rabbit urinary bladder epithelium.”

“The results establish that polypeptide growth factors have significant and selective positive influences on healing of full thickness ulcers in the rabbit.”

“Thus, it was demonstrated that administration of pineal polypeptides to the rabbit lowers the urinary 17-KS both of testicular and adrenal origin.”

“An antiserum against the polypeptide L3 was raised in a rabbit.”

“The three polypeptides increased the refractory period of isolated rabbit atria; in the case of oxytocin and lysyl vasopressin, this effect appears to be related to the chlorobutanol found in the vehicle normally used with these drugs.”