Possible Interaction: Polypeptides and Calcium Supplement

“However, trypsin degradation of the 80 kDa polypeptide , resulting in the loss of calcium transport activity and 32P-phosphoenzyme formation, is rapid in the presence of calcium , inhibited by EGTA and almost fully blocked by EGTA + vanadate.”

“It was shown that the polypeptide inhibits the increase of the concentration of calcium ions in mouse bone marrow derived macrophages elicited by histamine, and reduces the content of NO in lipopolysaccharide stimulated macrophages.”

“Hence, the translocating AC polypeptide itself appears to participate in formation of a novel type of membrane path for calcium ions , contributing to action of CyaA in an unexpected manner.”

“A small group of polypeptides in the 26-58 kDa range exhibited a dramatic increase in phosphorylation in the presence of 20 microM free calcium.”

“Although IL 2 and IL 3 share neither amino acid structural homologies nor cellular tissue specificity, both recombinant polypeptides induced rapid influx of calcium into quiescent cells bearing specific receptors for the ligand.”

“Intraduodenal infusions of calcium , magnesium, and zinc significantly stimulated CCK-33, PP , and gastrin release.”

“A strong binding of both proteins and their fragments corresponding to the NH2-terminal halves of polypeptide chain of respective proteins in the presence of calcium ions was observed.”

“It is concluded that the secretion of PP is influenced by calcium ions ; however, the PP release is much less dependent on extracellular calcium ions than are insulin and glucagon secretions.”

“Thus calcium , producing a significant gain of antibody affinity and titer in some antisera, can improve the sensitivity of radioimmunoassay of polypeptides.”

“We show that addition of calcium at concentrations between 50 and 500 mM imparts sufficient amphiphilicity to the diblock polypeptide between 33 and 46 °C to trigger its self-assembly into monodisperse spherical micelles with a hydrodynamic radius of ∼50 nm.”