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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Polymyxin B
supplement:
Resveratrol
Research Papers that Mention the Interaction
“Checkerboard analysis indicated … synergistic effect between resveratrol … polymyxin B ; the optimal drug concentration for different bacteria was different, that of resveratrol ranging from 32 μg/mL to 128 μg/mL. Subsequent time-kill experiments showed that a combination of polymyxin B and resveratrol was more effective in killing bacteria.”
“Conclusions Our in vitro studies have shown that resveratrol can increase the sensitivity of MDR bacterial strains to polymyxin B , suggesting a potential new approach to the treatment of MDR infections.”
“MICs against polymyxin B in the isolates tested were significantly reduced by the addition of resveratrol.”
Resveratrol enhances the antimicrobial effect of polymyxin B on Klebsiella pneumoniae and Escherichia coli isolates with polymyxin B resistance
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