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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Plicamycin and Magnesium Cation

Research Papers that Mention the Interaction

Results from different laboratories have shown that at and above physiological pH, Mg2+ is an obligatory factor for the DNA binding and subsequent transcription inhibitory property of mithramycin.
Journal of inorganic biochemistry  •  2005  |  View Paper
Mithramycin (MTR) is an anti-cancer antibiotic that blocks the macromolecular biosynthesis via reversible interaction with DNA template in the presence of bivalent metal ion such as Mg2+.
Indian journal of biochemistry & biophysics  •  2001  |  View Paper
Mithramycin is an anticancer drug that blocks macromolecular synthesis via reversible interaction with the DNA template in the presence of bivalent metal ions such as Mg2+.
Biochemistry  •  1995  |  View Paper