Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 months ago

Possible Interaction: Plicamycin and Calcium Supplement

Research Papers that Mention the Interaction

Mithramycin induced a significant decline in calcium levels and significant elevations of calciotrophic hormones (intact PTH, mid-region specific PTH, calcitonin and calcitriol).
Clinical endocrinology  •  1992  |  View Paper
In contrast, the introduction of intravenous mithramycin , brought about a reduction in serum alkaline phosphatase, urinary hydroxyproline excretion and urinary calcium.
Irish journal of medical science  •  1988  |  View Paper
Forced diuresis, cortisone and mithramycin can be used therapeutically to achieve a rapid fall in calcium level.
Deutsche medizinische Wochenschrift  •  1980  |  View Paper
Mithramycin at sub-tumoricidal doses inhibits the release of calcium mediated by osteoclasts.
Oncology  •  1982  |  View Paper
Furthermore, mithramycin A (a Sp1 inhibitor) prevented the upregulation of VDR mRNA by high calcium.
American journal of physiology. Renal physiology  •  2010  |  View Paper