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“In the isolated acini, pirenzepine did not have any significant effect on cholecystokinin-inducec amylase release but caused an inhibition of amylase secretion initiated by secretin and shifted the dose-response curve for amylase secretion to the right.”
“The stimulatory effect of both cholecystokinin octapeptide and secretin on insulin secretion was also inhibited by pirenzepine.”
Digestive Diseases and Sciences • 2005 | View Paper
“ Basal pancreatic secretion was decreased by atropine, pirenzepine , and hexamethonium and to a lesser extent by vagotomy (protein output decreased more than fluid and HCO3- outputs).”