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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Pirenzepine and Calcium Supplement

Research Papers that Mention the Interaction

The secretagogue acetylcholine (ACh) stimulated calcium mobilization from intracellular calcium stores at the base … EC50 of 14 μM. The muscarinic receptor antagonists 4‐DAMP, AF‐DX 384, pirenzepine … calcium signal with the following respective IC50 (pKb) values: 0.78 nM (…), 128 nM (7.1), and 2510 nM (5.8).
British journal of pharmacology  •  2002  |  View Paper
The Ca2+ response could partially be blocked by atropine and completely by pirenzepine , a specific muscarinic receptor-type M1 antagonist.
Hepatology  •  1997  |  View Paper
The carbachol effects depended on the calcium concentration and were competitively inhibited by pirenzepine.
European journal of pharmacology  •  1983  |  View Paper