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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Pirarubicin
supplement:
Theanine
Research Papers that Mention the Interaction
“ Theanine and DTBrC significantly enhanced the repression of HHC cell growth in combination with anticancer drug pirarubicin.”
Repression of Human Hepatocellular Carcinoma Growth by Regulating Met/EGFR/VEGFR-Akt/NF-κB Pathways with Theanine and Its Derivative, (R)-2-(6,8-Dibromo-2-oxo-2H-chromene-3-carboxamido)-5-(ethylamino)-5-oxopentanoic Ethyl Ester (DTBrC).“Moreover, theanine , which inhibited the pirarubicin efflux from M5076 cells, increased by 1.3‐fold the pirarubicin concentration in the tumor and enhanced the therapeutic efficacy of pirarubicin 1.7‐fold.”
Membrane Transport and Antitumor Activity of Pirarubicin, and Comparison with Those of Doxorubicin
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