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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Piperine
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Further, binding energy of Piperine was calculated by high-throughput MM-PBSA which states that calcium ion presence enhances the Piperine binding by additional electrostatic interactions.”
Exploring the binding mechanism and kinetics of Piperine with snake venom secretory Phospholipase A2“ Piperine reduced the activity of calcium release in the ER, and reduced the pump activity of calcium in the cytomembrane or enhanced the pump activity of Ca2+-ATPase in the ER.”
“We reported here in that appropriate concentration of PIP effectively inhibites the synchronized oscillation of intracellular calcium in rat hippocampal neuronal networks and represses spontaneous synaptic activities in terms of spontaneous synaptic currents (SSC) and spontaneous excitatory postsynaptic currents (sEPSC).”
“ Piperine also inhibited the influx of calcium into sperm during capacitation.”
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