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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Pimozide
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“With Y-1 plasma membranes it was found that trifluoperazine, pimozide , W-7, and calmodulin antibodies inhibited the increase in adenylate cyclase activity in response to ACTH , but not the cyclase responses to cholera toxin or forskolin.”
The role of calmodulin in the responses to adrenocorticotropin of plasma membranes from adrenal cells.“ Pimozide caused a slight rise in ACTH levels in some dogs.”
“Penfluridol, pimozide , and trifluoperazine blocked the release of ACTH induced by CRF by 63%, 26%, and 0% respectively.”
“Aldo responses to ACTH were more sensitive to inhibition by pimozide than those to 8-Br-cAMP, suggesting that ACTH-induced cAMP formation is also dependent on CM.”
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