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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Pimagedine
supplement:
Ferric Ion
Research Papers that Mention the Interaction
“Pretreatment with aminoguanidine (an inhibitor of NO synthase), N-methyl-D-glucamine dithiocarbamate complex with iron ion (II) (Fe2+(MGD)2, a trapping reagent of NO) or deferoxamine complex with iron ion (III) (Fe3+-deferoxamine, a scavenger of NO) produced a marked inhibition of the hepatotoxicity induced by cocaine.”
Cocaine-induced liver injury in mice is mediated by nitric oxide and reactive oxygen species.“In fact, the most stable complex of Fe(III) with AG , having a ∆Gf° of −37.9 kcal/mol, can reduce the rate constant of this reaction by 7.9 × 105 times.”
Theoretical Study of the Iron Complexes with Aminoguanidine: Investigating Secondary Antioxidant Activity“We could detect hydroxyl radical as well as hydrogen peroxide during the incubation of AG with Fe+3.”
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