Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 5 months ago

Possible Interaction: Phytate and Iron, Dietary

supplement:

Phytate

supplement:

Iron, Dietary

Research Papers that Mention the Interaction

BACKGROUND Weaning foods frequently contain phytate , an inhibitor of iron and zinc absorption, which may contribute to the high prevalence of iron and zinc deficiency seen in infancy.
The American journal of clinical nutrition  •  2003  |  View Paper
The inhibition of Fe absorption was strongly related to the amount of phytate added; 2 mg inhibited absorption by 18%, (p less than 0.001), 25 mg by 64% (p less than 0.001), and 250 mg by 82% (p less than 0.001).
The marked inhibition of Fe absorption by phytates and the significant counteracting effect of ascorbic acid have wide nutritional implications.
The American journal of clinical nutrition  •  1989  |  View Paper
All the nuts tested contained significant amounts of two known inhibitors of Fe absorption ( phytates and polyphenols) but the amounts in coconut were significantly less than in the other nuts.
The American journal of clinical nutrition  •  1988  |  View Paper
Together, InsP6 acid and its salts are termed phytate " and are potent inhibitors of iron and zinc absorption.
Nutrition reviews  •  2018  |  View Paper
This complexity has mostly been attributed to the inhibitory effect of Fe and Zn binding by phytate , the principal phosphorus storage compound in cereal and legume seeds.
Plant science : an international journal of experimental plant biology  •  2014  |  View Paper
Common bean (Phaseolus vulgaris L.), the staple crop of Nicaragua, provides protein and nonhaem iron, but inhibitors such as phytate may prevent absorption of iron and zinc by the consumer.
Food chemistry  •  2013  |  View Paper
Based on the hypotheses that (1) Ca and Fe both promote Zn absorption by binding with phytate and thereby making it unavailable for binding Zn and (2) protein enhances the availability of Zn for transporter binding, the model was modified to incorporate these effects.
The British journal of nutrition  •  2013  |  View Paper
A negative correlation among phytate and Fe availability was found when increased levels of amaranth.
Plant Foods for Human Nutrition  •  2012  |  View Paper
Such foods are high in phytate , which limits the bioavailability of nutrients, including iron , calcium, zinc, and in some cases proteins, which are crucial to the development of infants.
Food and nutrition bulletin  •  2012  |  View Paper
Non-nutrient food constituents, such as, phytate and polyphenols interfere with the bioavailability of iron and zinc.
Asia Pacific journal of clinical nutrition  •  2008  |  View Paper
Show More