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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Physostigmine
supplement:
Quinidine
Research Papers that Mention the Interaction
“It appears that the binding of Phy to human plasma proteins was altered to a significant degree in the presence of quinidine , furosemide, acetaminophen, theophylline and verapamil.”
“… Phy to plasma … of quinidine (3-15 micrograms/ml), from 45.5-5.3%, furosemide (1-100 micrograms/ml) from 45.5-28.4%, acetaminophen (10-160 ….9%, theophylline (6.67-80 micrograms/ml) 52.2-43.7%, verapamil (0.1-0.5 micrograms/ml) 44.8-34.9%.”
Drug interaction for plasma protein binding: physostigmine and other drugs.“In contrast, the ability of quinidine to antagonize the negative chronotropic effects of physostigmine was non-stereoselective, quinidine = quinine.”
Anticholinergic Effects of Disopyramide and Quinidine on Guinea Pig Myocardium: Mediation by Direct Muscarinic Receptor Blockade
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