Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 5 years ago

Possible Interaction: Phosphoserine and Serine

supplement:

Phosphoserine

supplement:

Serine

Research Papers that Mention the Interaction

“Here, the authors show that it promotes proliferation of T-ALL cells by upregulating the serine biosynthesis enzyme phosphoserine phosphatase which in turn modulates serine and glycine metabolism.”
Nature Communications  •  2019  |  View Paper
“ Serine in physiological concentrations inhibits P-serine phosphatase , the last reaction in the “phosphorylated pathway”.”
Advances in enzyme regulation  •  1967  |  View Paper
“Inhibition of P-serine phosphatase by l-serine may have physiological significance in mammals.”
The Journal of biological chemistry  •  1966  |  View Paper
“In addition, reactive DESI can be performed with ion/ion reactions of Zn(II) complexes for the selective binding of phosphoserine in the presence of serine.”
Journal of the American Society for Mass Spectrometry  •  2009  |  View Paper
“For optimal conditions the reaction of O-phosphoserine is faster by a factor of 10(4) in the velocity of the beta-elimination than the corresponding acid-catalyzed beta-elimination of serine.”
Biochimica et biophysica acta  •  1976  |  View Paper