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“ Human phosphoserine phosphatase (HPSP) regulates the levels of glycine and d-serine , the putative co-agonists for the glycine site of the NMDA receptor in the brain.”
The Journal of Biological Chemistry • 2002 | View Paper
“Our study suggests that L-phosphoserine phosphatase may play a role in altered neuronal function in AD via enhancing glutamate-induced neurotoxicity by D-serine and the IL-11 receptor system may act as a neuroprotective cytokine in human brain.”