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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Phosphorus and Tretinoin

supplement:

Tretinoin

Research Papers that Mention the Interaction

ResultsThe retinoic acid administration decreased the bone mass and the contents of calcium and phosphorus in the bone mineral, weakened the biomechanical properties, and increased bone turnover by stimulating bone resorption and collagen metabolism.
BMC Complementary and Alternative Medicine  •  2015  |  View Paper
In fact, the retinoid induced the activation of the apoptotic cascade related to the generation of ROS through endoplasmic reticulum stress response and upregulation of phospho c-Jun N-terminal kinases and PLAcental Bone morphogenetic protein, leading to cell death through caspase-3 cleavage.
Front. Pharmacol.  •  2017  |  View Paper