Possible Interaction: Phosphorus and Phosphorus, Dietary

“BACKGROUND Control of dietary phosphate absorption in end-stage renal disease patients is essential to prevent the deleterious sequelae of phosphorus retention.”

“ Dietary phosphorus intake and the phosphorus density of the diet are increasing.”

“The high dietary phosphorus load increased serum phosphorus at 2 h and significantly decreased flow-mediated dilation.”

“Effective strategies to control dietary phosphorus intake include restricting phosphorus-rich foods, preferring phosphorus sourced from plant origin, boiling as the preferred cooking procedure and avoiding foods with phosphorus-containing additives.”

“Because hemodialysis treatment has a limited ability to remove phosphorus, dialysis patients must restrict dietary phosphorus intake and use phosphorus binding medication.”

“The importance of phosphorus in the poor patient outcomes associated with untreated CKD-MBD is supported by the evidence that reduction of serum phosphorus , through the use of dietary phosphorus binders , improves patient survival (6–8).”

“Restriction of the dietary intake of phosphorus increases renal phosphate reabsorption and 1,25(OH)(2)D production, whereas the opposite occurs when dietary phosphorus is supplemented.”

“Therefore, to prevent phosphorus retention , we must first decrease dietary phosphorus , which results in less absorption and is always worthwhile but limited by …”

“Independent of these effects, renal failure–mediated phosphate retention and dietary phosphorus lead to increased serum phosphorus levels.”

“… dietary phosphorus induced: (a) a 58% increase in serum levels of 1,25(OH)2D; (b) a 35% decrease in serum … of phosphorus measured in the afternoon; (c) a 12% decrease in the 24-h mean serum level of phosphorus ; but, (d) no decrease in … fasting levels of phosphorus.”