Possible Interaction: Phosphorus and Calcium Supplement

“It is therefore essential to take precautions as to possible increases in calcium and phosphorus.”

“Urinary excretion of calcium increased and serum level of phosphorus reduced after oral administration of calcium.”

“ Serum phosphorus was significantly lower in the calcium group throughout the study (P = 0.02).”

“We conclude that very low birth weight infants fed high calcium may require greater phosphorus intake than that provided by formulas containing a ratio of calcium to phosphorus of 2:1.”

“During intervention, calcium, magnesium, phosphorus , potassium, thiamin, riboflavin, and vitamins C and D increased (P < 0.01) in the group receiving food calcium but not in the placebo or supplement groups.”

“A complementary study in male mice also demonstrated that the regulation of known dietary phosphorus responsive factors was mostly abrogated when dietary calcium was raised in parallel with phosphorus.”

“When aortic rings from normal rats or a primary culture … with phosphorus or vitamin D analogs in vitro, high phosphorus … calcium accumulation and/or 45Ca uptake in a dose- or time-dependent manner, whereas vitamin … nM had no significant effect despite the presence of a functional vitamin D receptor.”

“The amounts of phosphorus intake with calcium are increasing from 1960 to 1995.”

“Considering the low renal capacity for acid excretion in newborns, a high intake of calcium and phosphorus is a risk factor for the development of metabolic acidosis.”

“There was a negative balance for both phosphorus and calcium with low serum levels of 1,25-dihydroxyvitamin D which were corrected by resection of the tumor.”