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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Phospholipids and Water-Soluble Vitamin

Research Papers that Mention the Interaction

In vitro, detergents (Triton X-100 or bile acids) or negatively charged ganglioside or phospholipids and one of several "activator proteins" increase hydrolytic rate of lipid and water-soluble substrates.
Critical reviews in biochemistry and molecular biology  •  1990  |  View Paper
Another perspective uses water-soluble additives , such as electrolytes and hydrophilic polymers that are prone to enhance adsorption of phospholipids.
Soft matter  •  2015  |  View Paper
Importantly, our studies indicate that PLC-NPs may be a promising delivery system to enhance the oral bioavailability of highly water-soluble drugs.
Molecular pharmaceutics  •  2010  |  View Paper
Water-soluble polymers such as dextran and polyethylene glycol are known to induce aggregation and size growth of phospholipid vesicles.
Biophysical journal  •  1996  |  View Paper
Water-soluble polymers , such as dextrans and polyethylene glycols (PEGs) of different molecular weights, induce reversible aggregation of phospholipid vesicles , mostly due to dehydration of the vesicle surface and depletion forces, and only at much higher concentrations, PEGs (but not dextran) also induce irreversible size growth of the vesicles.
Biophysical journal  •  1996  |  View Paper
By coadmixing a small amount of negatively charged phospholipids such as dipalmitoyl phosphatidylglycerol or dicetyl phosphate, the leakage of water-soluble NA was further prevented.
Journal of pharmaceutical sciences  •  1994  |  View Paper