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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Phospholipids
supplement:
Tocopherols
Research Papers that Mention the Interaction
“When present in biological membranes, tocols will experience a large variation in the local composition of phospholipids and the presence of neutral lipids such as cholesterol, both of which would be expected to change the efficiency of antioxidant action.”
Tocopherols and tocotrienols in membranes: a critical review.“The rates of decrease of Toc were faster than that of PL.”
“ Phospholipids have been shown to act synergistically with tocopherols and delay lipid oxidation in bulk oil.”
“The synergistic activity between phospholipids and tocopherols is due to the ability of amino-group-containing phospholipids (e.g., phosphatidylethanolamine (PE) and phosphatidylserine (PS)) to convert oxidized tocopherol back into tocopherols.”
Impact of Phospholipids and Tocopherols on the Oxidative Stability of Soybean Oil-in-Water Emulsions.“The phospholipid form of n-3 PUFA increased the level of tocopherols in epididymal adipose tissue compared with HF-ω3TG and resulted in smaller adipocytes than the two others HF groups.”
“ Tocopherols with shorter or longer side chains than alpha-tocopherol had a lesser ability to penetrate monolayers of phospholipid molecules with 16 or more carbon atoms in their acyl chains.”
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