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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phospholipids
supplement:
Quinine
Research Papers that Mention the Interaction
“Conclusions: Quinine triggers phospholipid scrambling of the erythrocyte cell membrane, an effect at least in part due to Ca2+ entry, oxidative stress, ceramide and D4476 sensitive casein kinase.”
Stimulation of Erythrocyte Cell Membrane Scrambling by Quinine“We found that quinine desorbed pre-formed β2GPI-aPL immunoglobulin (Ig)G complexes from phospholipid bilayers at significantly lower molar concentrations than HCQ.”
“The responses to quinine hydrochloride and L-tryptophan, which have a bitter taste, were reduced as the phospholipid concentration was increased, and the responses to the other taste substances were not affected by the phospholipids, as with the human sensation test.”
“In contrast, these three drugs were unable to modify phosphatidylserine synthesis, indicating that the K+ channel blockers, quinine and quinidine, specifically interfere with the synthesis of this phospholipid.”
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