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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phospholipids
supplement:
Quercetin
Research Papers that Mention the Interaction
“ Quercetin in a delivery-food grade system with sunflower phospholipids (Quercetin Phytosome®, QP) increases its oral absorption up to 20-fold.”
Possible Therapeutic Effects of Adjuvant Quercetin Supplementation Against Early-Stage COVID-19 Infection: A Prospective, Randomized, Controlled, and Open-Label Study“CONCLUSION This study showed that nanoliposomal encapsulation in ri e-bran phospholipids en hanced the radical-scavenging and anti-angiogenic activities of que rcetin. ”
Enhanced bioactivity and efficient delivery of quercetin through nanoliposomal encapsulation using rice bran phospholipids.“ Quercetin and luteolin also inhibited enhancement of 32Pi-incorporation into phospholipid by dihydroteleocidin B, another potent tumor promoter.”
“In this study, we intended to improve the bioavailability of QT by preparing quercetin-phospholipid complex (QT-PC) and investigate the protective effect of QT-PC against carbon tetrachloride (CCl4) induced acute liver damage in Sprague-Dawley (SD) rats.”
“Thus, phospholipid complexation might be one of the suitable approaches to improve the oral bioavailability of QT and obtain better protective effects against CCl4 induced acute liver damage in SD rats than free QT at the same dose level.”
Development of quercetin-phospholipid complex to improve the bioavailability and protection effects against carbon tetrachloride-induced hepatotoxicity in SD rats.“However, 8-anilinonaphthalene sulphonate-binding assay revealed that quercetin marginally affected the interaction between active site of PLA2 with phospholipid vesicles.”
“ Quercetin pretreatment also significantly (P<0.05) reduced the levels of total cholesterol, triglycerides and free fatty acids in serum, heart and heart mitochondria and serum phospholipids in isoproterenol treated cardiotoxic rats.”
“ Quercetin and alpha-tocopherol significantly reduced the levels of cholesterol, triglycerides and free fatty acids in the serum and heart and serum phospholipids and significantly increased the levels of heart phospholipids in isoproterenol induced rats.”
“ Quercetin significantly lowered serum cholesterol and phospholipid levels in mice.”
“Results showed that the solubility of quercetin in Coil increased up to 7.7-fold by phospholipid addition.”
“Chalcones (phloretin and phloridzin) and flavonols quercetin and myricetin) strictly decrease the dipole potential of phospholipid- and sterol-containing membranes; the unsaturation of the C-ring and the hydrophobicity of the molecule contribute to the ability of the flavonoid to reduce the bilayer dipole potential.”
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