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“However, the presence of some specific, highly hydrophobic polypeptides is essential to modulate the physical behavior of phospholipids and to promote rapid formation of stable surface films that are able to produce surface tensions in the range of 0 dynes/cm during cyclic compression.”
Pediatric pathology & molecular medicine • 2001 | View Paper
“This effect was inhibited by anionic polypeptide fraction , which increased the amount of cholesterol within precipitable phospholipid vesicles , and decreased the rate of crystal formation.”
“Phospholipid binding was not affected by these modifications, but their binding preference was determined by the electrostatic interactions between the polypeptide and phospholipid.”
“These polypeptides are known to alter the membrane matrix by binding to phospholipid , and we suggest that this alteration allowed greater access of substrate and of nitroprusside to the enzyme.”
“Electrostatic binding of proteins and basic polypeptides to the (anionic) polar groups of phospholipids shifts the temperature of the gel-liquid crystal transition of the lipid and also affects the energy barrier for reorientation of a spin label in the hydrocarbon phase.”
“Knowledge of the structure, dynamics and interactions of polypeptides when associated with phospholipid bilayers is key to understanding the functional mechanisms of channels, antibiotics, signal- or translocation peptides.”
“Presumably, formation of a complex between the polypeptide and phospholipids may decrease the actual concentration of gramicidin S in cells producing the antibiotic.”
“We present evidence that at temperatures greater than their main transition temperature, phospholipid molecules that are trapped within clusters of intrinsic molecules such as polypeptides or proteins have the ends of their hydrocarbon chains more statically disordered than those of lipid molecules far from such intrinsic molecules.”
“Reversible interactions were demonstrated between some phospholipids and some polypeptides related to angiotensin and bradykinin.”
“The phospholipids altered the chromatographic behavior of radioiodinated derivatives of the polypeptides , and solubilized radioactive and unlabeled polypeptides in chloroform.”