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Possible Interaction: Phospholipids and Phosphatidylinositol 4,5-Diphosphate

Research Papers that Mention the Interaction

PIP2 also increased the spontaneous solubilization of phospholipid liposomes by apoA1.
Circulation research  •  2016  |  View Paper
We report that PIP2 can redistribute intracellular cations and thereby lead to a loss of phospholipid asymmetry.
Biochemistry  •  1998  |  View Paper
Phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate activate PLD1a and 1b but a range of other acidic phospholipids are ineffective.
The Journal of Biological Chemistry  •  1997  |  View Paper
Addition of PtdIns(4,5)P2 increased PLD activity in HEK cell membranes by 2-3-fold, whereas various other phospholipids were ineffective.
European journal of biochemistry  •  1996  |  View Paper
Increasing the molar ratio of anionic phospholipid by adding phosphatidylserine, additional PtdIns(4,5)P2 , or by situating PtdIns(4,5)P2 in a more physiologically relevant lipid background increased the apparent association rate constant less than 2-fold.
The Journal of Biological Chemistry  •  2009  |  View Paper
However, soybean phospholipids asolectin and phosphatidylinositol-4,5-bisphosphate [ PtdIns(4,5)P2 ] strongly inhibited the binding activity.
Journal of biochemistry  •  1992  |  View Paper
Analysis of the dependence of … free Ca2+ concentration showed that acidic phospholipids increased Vmax and lowered the apparent Km for free Ca2+ … upon tryptic cleavage of the CaM-binding domain; in particular, PIP2 was shown to lower the apparent Km for … the Ca2+-ATPase also in trypsin-treated PM.
Physiologia plantarum  •  2001  |  View Paper