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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Phospholipids
supplement:
Linolenic Acid
Research Papers that Mention the Interaction
“ ALNA supplementation increased the proportion of EPA but not DHA in plasma phospholipids.”
Comparison of the effects of linseed oil and different doses of fish oil on mononuclear cell function in healthy human subjects.“We showed that in a population with low intakes of LA and ALA, the proportions of phospholipid LA and ALA determines the relative proportions of AA and DHA and low iron status probably attenuates the conversion of LA to AA.”
“We found that 2 g/d of -linolenic acid given to previously obese women increased the arachidonate content of their serum phospholipids [2].”
“When the polyunsaturated fatty acid content of the phospholipids was increased by supplementing the medium with linolenic or docosahexaenoic acids (n‐3 polyunsaturates) or linoleic or arachidonic acids (n‐6 polyunsaturates), the K′m and V′max of the high‐affinity glycine uptake system were increased three‐ to fourfold.”
“ Dietary trans alpha-linolenic acid altered the fatty acid composition of retinal and hepatic phospholipids by significantly increasing the Delta19trans-isomer of docosahexaenoic acid.”
“Animal and human studies have indicated that developing mammals fed only alpha-linolenic acid (18:3n-3) have lower docosahexaenoic acid (22:6n-3) content in brain and tissue phospholipids when compared with mammals fed 18:3n-3 plus 22:6n-3.”
Comparative bioavailability of dietary alpha-linolenic and docosahexaenoic acids in the growing rat.“The results suggest that the small increase in the proportion of n-3 fatty acids in the sperm phospholipids induced by enriching the diet with alpha-linolenic acid is associated with a significant improvement in semen quality at 39 weeks of age.”
“ Hepatic phospholipids were significantly higher in the alpha-linolenic acid and arachidonic acid group as compared to the linoleic acid group.”
“The concentration of serum triglyceride, phospholipid and liver triglyceride were significantly lower in the alpha-linolenic acid and arachidonic acid groups than in the linoleic acid group.”
“Linoleic and alpha-linolenic acid treatments reduced total phospholipid and cholesterol content of the testicular plasma membrane and altered membrane phospholipid composition.”
“The (n-6), (n-3) fatty acid spectra in heart and liver phospholipids are strongly affected when linolenic acid is added to the diet whereas erucic acid has little effect.”
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