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Last Updated: 2 years ago

Possible Interaction: Phospholipids and Iron, Dietary

Research Papers that Mention the Interaction

Ferroptosis is a recently characterized cell death phenotype resulting from iron catalyzed peroxidation of polyunsaturated fatty acid (PUFA) phospholipids.
Rejuvenation research  •  2020  |  View Paper
LOOH molecules and iron ions at the cell wall of an injured cell are in tight contact with phospholipids of neighboring cells and transfer to these reactive radicals.
Molecular nutrition & food research  •  2005  |  View Paper
First, catechols (including dopa and dopamine) and iron form strong oxidizing complexes and induce lipid peroxidation (LPO) in phospholipid liposomes.
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics  •  1997  |  View Paper
Searching for physiologically relevant lipid regulators of Cygb, here we report that anionic phospholipids , particularly phosphatidylinositolphosphates, affect structural organization of the protein and modulate its iron state and peroxidase activity both conjointly and/or independently of cysteine oxidation.
Biochimica et biophysica acta  •  2016  |  View Paper
Cellular accumulation of ionic iron leads to peroxidative decomposition of organelle membrane phospholipids with the consequence of cell degeneration and cell death.
European journal of clinical investigation  •  1993  |  View Paper
Acidic phospholipids , such as phosphatidylinositol (PI) and phosphatidylserine (PS), were observed to show an inhibited acylation profile in retinas exposed to iron while phosphatidylethanolamine (PE) showed the opposite.
Experimental eye research  •  2013  |  View Paper
In contrast to hypoxia, Ca2+ ionophore and Fe each induced significant PL losses (6 to 15%) despite minimal FFA accumulation or cell death (26 to 27% LDH release).
Kidney international  •  1999  |  View Paper
Dietary iron overload damages membrane phospholipids and decreases microsomal cytochromes P-450.
Alcoholism, clinical and experimental research  •  1999  |  View Paper
It therefore seemed of interest to investA-gate the synthesis, localization and effects on metabolism of phosphono lipids in Tetrahymena pyriformis grown in the presence of iron.
The Journal of nutrition  •  1971  |  View Paper
In conclusion, the results obtained indicate that iron ions interact with phospholipid bilayers perturbing their structures.
Chemistry and physics of lipids  •  2005  |  View Paper
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